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New strategies for the prevention and treatment of immune injury in liver transplantation
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Zhengli TAN, Qiang LIU, Yanyao LIU*
Science & Technology Review | 2026, 44(11) : 33 - 41
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Science & Technology Review | 2026, 44(11): 33-41
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New strategies for the prevention and treatment of immune injury in liver transplantation
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Zhengli TAN, Qiang LIU, Yanyao LIU*
Affiliations
  • Department of Hepatobiliary Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Published: 2026-06-13 doi: 10.3981/j.issn.1000-7857.2025.06.00058
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Liver transplantation is the only effective treatment for various end−stage liver diseases. However, immune injury after liver transplantation, such as acute rejection (AR), chronic rejection (CR), hepatic ischemia−reperfusion injury (HIRI), and opportunistic infection, still seriously affects the prognosis of patients. Although great progress has been made in the research of immune injury after liver transplantation, there are still many deficiencies in clinical practice. In this article, the functional changes of hepatocytes and non−parenchymal cells after liver transplantation were used as the breakthrough point to summarize and clarify the potential molecular mechanisms of immune injury after liver transplantation, systematically review the latest progress in the prevention and treatment of immune injury after liver transplantation, and focus on emerging prevention and treatment strategies and their clinical application prospects. The application of artificial intelligence and big data technology in the prediction, diagnosis, treatment and management of immune injury in liver transplantation is prospected, in order to provide reference for related basic research and clinical application.

liver transplantation  /  immune damage  /  acute rejection  /  ischemia−reperfusion injury  /  immune cells
Zhengli TAN, Qiang LIU, Yanyao LIU. New strategies for the prevention and treatment of immune injury in liver transplantation[J]. Science & Technology Review, 2026 , 44 (11) : 33 -41 . DOI: 10.3981/j.issn.1000-7857.2025.06.00058
Year 2026 volume 44 Issue 11
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doi: 10.3981/j.issn.1000-7857.2025.06.00058
  • Receive Date:2025-06-05
  • Online Date:2026-06-23
  • Published:2026-06-13
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  • Received:2025-06-05
  • Revised:2025-12-24
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    Department of Hepatobiliary Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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