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A high−sensitivity multi−resonant terahertz metasurface biosensor for cancer cell detection
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Yujie HUANG1, 2, Yafeng HAO1, 2, Yuhang LIU2, Wenyu NIU1, 2, Tengteng LI1, 2, *
Science & Technology Review | 2026, 44(9) : 116 - 123
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Science & Technology Review | 2026, 44(9): 116-123
• Papers •
A high−sensitivity multi−resonant terahertz metasurface biosensor for cancer cell detection
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Yujie HUANG1, 2, Yafeng HAO1, 2, Yuhang LIU2, Wenyu NIU1, 2, Tengteng LI1, 2, *
Affiliations
  • 1State Key Laboratory of Widegap Semiconductor Optoelectronic Materials and Technologies, North University of China, Taiyuan 030051, China
  • 2School of Semiconductor and Physics, North University of China, Taiyuan 030051, China
Published: 2026-05-13 doi: 10.3981/j.issn.1000-7857.2026.03.00062
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Conventional biological detection methods typically suffer from drawbacks such as long detection duration, low detection efficiency, and insufficient sensitivity. Terahertz (THz) metasurface sensors exhibit promising application potential in the field of biosensing owing to their merits of label−free detection, non−invasiveness, and high sensitivity. Aiming at the issues of single resonant mode and unsatisfactory performance of existing THz metasurface biosensors, a multi−resonant THz metasurface biosensor is proposed in this work. The device generates three narrowband high−absorption resonant peaks at 2.933, 3.412, and 3.637 THz, respectively. Within the refractive index range of 1~1.40, the resonant frequencies display a red−shift with the increase in refractive index. The maximum refractive index sensitivities of the resonant peaks at 2.933 and 3.412 THz are 541 and 981 GHz/RIU, with ultra−high quality factors of 320 and 82, respectively. The THz metasurface structure designed in this study holds broad application prospects for the highly sensitive biomedical detection of cancer cells and their related biomarkers.

terahertz  /  metasurfaces  /  biosensing  /  cancer cell detection  /  high−sensitivity  /  high−Q factor
Yujie HUANG, Yafeng HAO, Yuhang LIU, Wenyu NIU, Tengteng LI. A high−sensitivity multi−resonant terahertz metasurface biosensor for cancer cell detection[J]. Science & Technology Review, 2026 , 44 (9) : 116 -123 . DOI: 10.3981/j.issn.1000-7857.2026.03.00062
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doi: 10.3981/j.issn.1000-7857.2026.03.00062
  • Receive Date：2026-03-27
  • Online Date：2026-05-27
  • Published：2026-05-13
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  • Received：2026-03-27
  • Revised：2026-04-15
Funding
Affiliations
    1State Key Laboratory of Widegap Semiconductor Optoelectronic Materials and Technologies, North University of China, Taiyuan 030051, China
    2School of Semiconductor and Physics, North University of China, Taiyuan 030051, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
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Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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