Leveraging its evolutionary capacity that surpasses biological intelligence, digital intelligence has irreversibly upended the traditional human–machine dynamic. Re–examining the fundamental relationship between humans and technology has become a philosophical imperative concerning humanity's own future. This paper traces the semantic origins of the Chinese term "She Ji" (design) and establishes a four–quadrant interactive framework grounded in the dialectical unity of "She"—which pertains to language and action—and "Ji"—which pertains to calculation and strategy. This framework is used to analyze design opportunities following the systematic "colonization" of creative fields by artificial intelligence: while AI has gained an absolute advantage in the domains of calculation and language, the unique value of humanity is embodied in action and strategy—encompassing emotional interaction, embodied experience, cultural strategy, and order construction. Confronted with this landscape, the mission of design has ascended from creating objects to reshaping the relationships and order of human–machine symbiosis. The core of future design lies in leveraging intelligent systems to their fullest while constructing a new value compass and civilizational compact, integrating the four domains of "Suan" (calculation), "Yan" (language), "Yi" (action), and "Ce" (strategy), to achieve a paradigm shift from goal attainment to order creation. This constitutes not only a practical pathway for human–machine collaboration but also points toward the construction of a new form of civilization—in this profound transformation, design can assume the role of "relationship architect" proactively, establishing sustainable principles for coexistence on a dual–track future.