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Current status, issues, and policy recommendations of biomanufacturing development in China
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Yanping YANG1, 2, Zhao LI1, Changrou LI1, 2, Hongxiang ZHANG1, 3, Guoqiang CHEN4, He HUANG5, 6, *
Science & Technology Review | 2026, 44(5) : 24 - 31
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Science & Technology Review | 2026, 44(5): 24-31
Special to S & T Review
Current status, issues, and policy recommendations of biomanufacturing development in China
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Yanping YANG1, 2, Zhao LI1, Changrou LI1, 2, Hongxiang ZHANG1, 3, Guoqiang CHEN4, He HUANG5, 6, *
Affiliations
  • 1National Science Library, Chinese Academy of Sciences, Beijing 100190, China
  • 2Department of Information Resources Management, School of Economics and Management, University of Chinese Academy of Sciences, Beijing 100190, China
  • 3Chinese Society of Biotechnology, Beijing 100101, China
  • 4Department of Chemical Engineering, School of Life Sciences, Tsinghua University, Beijing 100084, China
  • 5School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China
  • 6Jiangsu Synthetic Biology Basic Research Center, Nanjing 210023, China
Published: 2026-03-13 doi: 10.3981/j.issn.1000-7857.2025.05.00151
Outline
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Biomanufacturing is increasingly recognized as a pivotal engine for global economic growth, with its strategic significance being emphasized by major economies worldwide. In this article, the conceptual connotation of biomanufacturing is systematically examined, followed by a comprehensive analysis of the international competitive landscape through the dual lenses of scientific and technological advancement and strategic policy frameworks. It also summarizes China's progress in scientific and technological achievements, innovation platforms, and industrial development. Four critical challenges confronting China's biomanufacturing sector are identified: 1) underdeveloped innovation capabilities in foundational generic technologies; 2) sustainable and low−cost feedstock sources remain inadequately explored; 3) systemic deficiencies and import dependencies persist in biomanufacturing equipment; and 4) shortage of interdisciplinary industrial talent is observed. To address these constraints, strategic recommendations aligned with national strategic needs (e.g., food security, energy security) are proposed. Through coordinated policy interventions and technological modernization, the following actions should be prioritized: basic research should be intensified to foster original innovation; breakthroughs in core proprietary technologies should be systematically pursued; commercialization of scientific and technological achievements ought to be accelerated and a diversified talent cultivation ecosystem needs to be established. Collectively, these measures are expected to furnish the scientific and technological foundation necessary for high−quality, resilient advancement of China's biomanufacturing sector.

biomanufacturing  /  future industries  /  new quality productive forces  /  synthetic biology  /  industrial strains  /  enzyme preparations  /  non−food feedstock  /  C1 compounds
Yanping YANG, Zhao LI, Changrou LI, Hongxiang ZHANG, Guoqiang CHEN, He HUANG. Current status, issues, and policy recommendations of biomanufacturing development in China[J]. Science & Technology Review, 2026 , 44 (5) : 24 -31 . DOI: 10.3981/j.issn.1000-7857.2025.05.00151
Year 2026 volume 44 Issue 5
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doi: 10.3981/j.issn.1000-7857.2025.05.00151
  • Receive Date:2025-05-12
  • Online Date:2026-04-10
  • Published:2026-03-13
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  • Received:2025-05-12
  • Revised:2025-09-04
Funding
Affiliations
    1National Science Library, Chinese Academy of Sciences, Beijing 100190, China
    2Department of Information Resources Management, School of Economics and Management, University of Chinese Academy of Sciences, Beijing 100190, China
    3Chinese Society of Biotechnology, Beijing 100101, China
    4Department of Chemical Engineering, School of Life Sciences, Tsinghua University, Beijing 100084, China
    5School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China
    6Jiangsu Synthetic Biology Basic Research Center, Nanjing 210023, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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