Since Kaplan et al.first proposed the concept of RWS in 1993, China has become a hot spot in the real world research of traditional Chinese medicine.How to effectively collect value data (RWD) related to patients, and how to make correct, efficient, and accurate statistics, induction, organization, and analysis of the data, making it evidence of use value, potential benefits, and potential risks (RWE) have become important research topics.Japan's "configuration (home) medicine (box)" and its comprehensive, three-dimensional, and multi-level "ledger" information accumulation model formed under various conditions have made real records, data statistics, information induction, observation and analysis, and objective judgments on the usage history, functional testing, and effect verification of more than 100 ancient classic Chinese herbal medicines for more than 300 years.They have completed the transformation of data accumulation into evidence and into real-world research results, providing strong support for the secondary development, improvement, and enhancement of Chinese herbal medicines.Under the theoretical framework of "value medicine", ancient classic Chinese herbal medicines have been used to "prevent diseases before they occur and prevent recurrence after they occur".The value cognition of "treating diseases before they occur" has been constructed as a quantitative means.Given the current situation of limited research in this field, it is recommended to strengthen the exploration of the background and historical evolution of Japan's real-world research on "configuration (home) medicine (box)", analyze its mode characteristics and unique value, summarize its enlightening and reference value, and provide reference for improving the quality and efficiency of real-world research.

ledger  /  drug seller  /  configure medicine boxes  /  classic formulas  /  Chinese herbal medicine  /  use first and then benefit  /  human experience  /  value healthcare