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An efficacy evaluation method for analyzing composite endpoints based on patient preference and it's implications for traditional Chinese medicine
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Science & Technology Review | 2024, 42(21) : 87 - 93
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Science & Technology Review | 2024, 42(21): 87-93
Exclusive: The paradigm and application of clinical research in traditional Chinese medicine
An efficacy evaluation method for analyzing composite endpoints based on patient preference and it's implications for traditional Chinese medicine
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LI Shuangjing1, YAN Shiyan1, LU Ying2
Affiliations
    1. College of Acupuncture and Massage, Beijing University of Chinese Medicine, Beijing 100010, China;
    2. Department of Biomedical Data Science, Stanford University School of Medicine, California 94305, USA
Published: 2024-11-13 doi: 10.3981/j.issn.1000-7857.2024.05.00474
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When composite endpoints are used as efficacy indicators in clinical efficacy evaluation, the same weight is usually assigned to each indicator for overall evaluation.In fact, different indicators are often of different importances for patients, and a simple comprehensive analysis cannot reflect the important concept of "patient-centered".To address these issues, this article introduces an efficacy evaluation method based on patient preference analysis of composite endpoints.By integrating multidimensional indicators (such as clinical efficacy indicators, patient-reported outcomes) while considering each patient preference, this method ranks different indicators, assigns varying importances, and compares efficacies of interventions.It is concluded that this method is suitable for the evaluation of complex intervention in traditional Chinese medicine and is compatible with the holistic view and individual treatment, which can reflect the clinical reality and the real diagnosis and treatment environment, and embody the real value of treatment to patients.It is suggested that in the future, the traditional Chinese medicine researchers should apply this method in efficacy evaluation scenarios with multiple composite indicators, patient-reported outcomes and real world.
patient preference  /  composite endpoint  /  desirability of outcome ranking  /  evaluation of traditional Chinese medicine clinical efficacy  /  real world study
LI Shuangjing, YAN Shiyan, LU Ying. An efficacy evaluation method for analyzing composite endpoints based on patient preference and it's implications for traditional Chinese medicine[J]. Science & Technology Review, 2024 , 42 (21) : 87 -93 . DOI: 10.3981/j.issn.1000-7857.2024.05.00474
Year 2024 volume 42 Issue 21
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doi: 10.3981/j.issn.1000-7857.2024.05.00474
  • Receive Date:2024-03-13
  • Online Date:2024-12-14
  • Published:2024-11-13
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  • Received:2024-03-13
  • Revised:2024-07-09
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
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占总种数比例
Percentage of
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Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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