Living heart, an emerging technology that integrates virtual reality (VR) with cardiac research, employs computational methods to simulate the physiological and pathological characteristics of heart, effectively replicating the real-time activities of a live-heart in terms of morphology, structure, and function. In this paper, the research progress of the key technologies of living heart in the visualization of cardiac anatomy, cardiac electrophysiological simulation model, and virtual heart organ-level coupling model is reviewed. The application prospect of living heart in cardiovascular disease pathogenesis, cardiovascular disease drug development, medical device research and development, medical teaching and clinical training is expected to provide new ideas for the realization of precision treatment of cardiovascular diseases.

living heart  /  virtual reality  /  medical imaging  /  angiocardiopathy  /  precision medicine