The International Space Station (ISS) continued to play its important role as an on-orbit scientific research and application platform. Comprehensive statistics and text analysis of the ISS experiments databases of the United States and Russia and annual highlights of results report showed the following findings. For the Expedition 66-67 from October 2021 to September 2022, NASA, Roscosmos, ESA, JAXA and CSA sponsored 360 experiments in six categories, including technology development and demonstration, biology and biotechnology, physical science, human research, educational and cultural activities, and earth and space science, of which new experiments accounted for more than 40%. At the same time, new scientific achievements, such as teleoperation by ISS crew to control robotic components on earth, creation and measurements of bubbles of ultracold atoms on-orbit, and observation of a magnetar, attracted widespread attention from the global science community. By focusing on representative new experiments and achievements this review comprehensively reflects the progress in the scientific research and application of ISS in this period, the progress of scientific research and application is comprehensively reflected. ISS is at the peak of scientific research and application output, with highly active research activities and continuous emergence of scientific achievements. In the future, it is expected to produce more new achievements to benefit space and Earth.

International Space Station  /  expedition  /  microgravity