The incidence of neurological diseases is increasing year by year, which seriously threatens human health and life. Ultrasound has been gradually applied to the treatment of brain diseases due to its non-invasiveness, high spatial resolution, mutiple stimulation targets, good MR compatibility effect and less adverse reactions. At present, the treatment of ultrasound neurological diseases mainly includes high-intensity focused ultrasound thermally lethal disease tissue, mechanical vibration to dissolve thrombus and low-intensity focused ultrasound stimulation therapy. This article briefly describes the development status of high-intensity focused ultrasound and its clinical applications in brain tumors, neuropathic pain, tremor, Parkinson, obsessivecompulsive disorder and stroke, as well as the development status of low-intensity focused ultrasound and its clinical applications in depression and epilepsy. Transcranial focused ultrasound can be used to treat neurological diseases noninvasively, but the impact of the skull needs to be fully considered.

focused ultrasound  /  transcranial  /  brain diseased