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Research progress on pharmacological role and mechanism of ursolic acid in nervous-mental system diseases
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Science & Technology Review | 2021, 39(13) : 117 - 124
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Science & Technology Review | 2021, 39(13): 117-124
• Review •
Research progress on pharmacological role and mechanism of ursolic acid in nervous-mental system diseases
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SHI Yajing1, LENG Yufang1,2, CHEN Feng1, ZHANG Jianmin1, REN Yixing1, LIU Xin1
Affiliations
    1. The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China;
    2. Department of Anesthesiology, the First Hospital of Lanzhou University, Lanzhou 730000, China
Published: 2021-07-13 doi: 10.3981/j.issn.1000-7857.2021.13.013
Outline
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Ursolic acid (UA) is a kind of pentacyclic triterpene acid compound found in a variety of plants, such as bearberries, privet leaves, and loquat leaves. In addition to the pharmacological effects of anti-oxidative, anti-inflammatory, anti-cancer, anti-diabetic, and hepatoprotective, UA also has the function of improving and treating many kinds of diseases in nervous-mental system. In this paper, the role of UA in neuronal injury, cerebrovascular diseases as well as mental disorders and its research mechanisms are summarized by literature analysis so as to provide reference for subsequent research and clinical application of UA in nervous-mental system diseases.
ursolic acid  /  nervous-mental system diseases  /  neuroprotection
石亚静, 冷玉芳, 陈凤, 张健民, 任以行, 刘馨. 熊果酸在神经精神系统疾病中的药理作用及机制研究进展. 科技导报, 2021 , 39 (13) : 117 -124 . DOI: 10.3981/j.issn.1000-7857.2021.13.013
SHI Yajing, LENG Yufang, CHEN Feng, ZHANG Jianmin, REN Yixing, LIU Xin. Research progress on pharmacological role and mechanism of ursolic acid in nervous-mental system diseases[J]. Science & Technology Review, 2021 , 39 (13) : 117 -124 . DOI: 10.3981/j.issn.1000-7857.2021.13.013
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Article Info
doi: 10.3981/j.issn.1000-7857.2021.13.013
  • Receive Date：2020-03-19
  • Online Date：2021-08-11
  • Published：2021-07-13
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  • Received：2020-03-19
  • Revised：2021-05-12
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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