Nanoselenium, as a new type of elemental selenium, has higher bioavailability, stronger biological activity and lower toxicity than organic selenium and inorganic selenium, and simultaneously has anti-oxidant and anti-tumor effects. This article mainly summarizes the application progress of selenium nanoparticles (SeNPs) in biomedicine, such as chemotherapy, radiotherapy, radio-chemotherapy and other clinical drugs to enhance the sensitization by SeNPs; the functionalization and targeted modification of SeNPs to enhance the anti-tumor effect; Se-nanomaterials in anti-tumor application; the toxicology of SeNPs; and the description of the industrialization research of SeNPs production. The review provides a guidance and support for the future nanoselenium production, study and research integration system.

selenium nanoparticles  /  tumour  /  accurate treatment