With the microfluidics, the precise control of micro-liquids and the miniaturized integration of multiple functionalities can be achieved, with incomparable advantages in the cell manipulation in terms of precision, efficiency and cost. Therefore, the microfluidics has become an interdisciplinary research hot spot in recent years. From the perspective of the cell manipulation methods and the corresponding applications, this paper reviews the latest progress in the field of the microfluidic cell manipulation, and discusses the advantages and disadvantages of various cell manipulation methods, and then analyzes the trend of the microfluidics based cell manipulation.

microfluidics  /  cell manipulation  /  cell sorting  /  cell enrichment  /  single-cell trapping