Glaucoma ranks the first in the irreparable blindness eye diseases in the world. As the elevated intraocular pressure is the main risk factor of visual impairment, decreasing intraocular pressure is the main treatment of glaucoma at present. Therefore, the biomechanical problem of glaucoma is an important part of the research of pathogenesis, prevention and treatment of glaucoma. The main reason of high intraocular pressure for glaucoma is the increase of outflow resistance of aqueous humor. The increase of intraocular pressure will lead to iris deformation, pupil block, change of flow field of aqueous humor in the anterior chamber, thinning thickness of optic nerve fiber layer and lamina cribrosa, and damage of visual function. Recent advances in glaucoma biomechanics are introduced from aspects of intraocular pressure measurement, measurement of aqueous humor flow, visual function imparied, etc.

elevated intraocular pressure  /  trabecular meshwork  /  aqueous humor  /  retina  /  visual function