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Progress in pathogenesis and treatment of Alzheimer's disease
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Science & Technology Review | 2017, 35(10) : 52 - 63
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Science & Technology Review | 2017, 35(10): 52-63
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Progress in pathogenesis and treatment of Alzheimer's disease
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ZHANG Heao, QING Hong
Affiliations
    School of Life Science, Beijing Institute of Technology, Beijing 100081, China
Published: 2017-05-28 doi: 10.3981/j.issn.1000-7857.2017.10.007
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Alzheimer's disease (AD) is a neurodegenerative disorder characterized by two pathological hallmarks:β-amyloid plaques and neurofibrillary tangles. It is the most common type of dementia and a common disease of the elderly. The pathogenesis of AD is related to multiple risk factors, pathways and molecular mechanisms. Because AD is a disease that is currently widespread in the elderly, it is essential to figure out pharmaceutical strategy for AD in order for aged people to get healthy and quality life. There is no treatment method that can completely cure AD right now, but there are various treatment strategies. This article reviews briefly the past and recent important findings of pathogenesis and treatment strategies of AD.
Alzheimer's disease  /  pathogenesis  /  amyloid β peptide  /  tau protein  /  treatment methods  /  treatment medicine
张贺奡, 庆宏. 阿尔茨海默症发病机制及治疗方法研究进展. 科技导报, 2017 , 35 (10) : 52 -63 . DOI: 10.3981/j.issn.1000-7857.2017.10.007
ZHANG Heao, QING Hong. Progress in pathogenesis and treatment of Alzheimer's disease[J]. Science & Technology Review, 2017 , 35 (10) : 52 -63 . DOI: 10.3981/j.issn.1000-7857.2017.10.007
Year 2017 volume 35 Issue 10
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doi: 10.3981/j.issn.1000-7857.2017.10.007
  • Receive Date:2016-01-07
  • Online Date:2017-05-25
  • Published:2017-05-28
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  • Received:2016-01-07
  • Revised:2016-09-01
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
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Percentage of
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Genus
种数
Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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