The relationship between the testing results of remnant functions of patients with consciousness disorder and their prognosis is an important issue. Our study focuses on the clinical value of the mismatch negativity(MMN) applied for predicting the consciousness recovery and the long-term prognosis of severe traumatic brain injury patients. A retrospective research considers 6 cases of DOC, induced by severe brain injury. The Mismatch Negativity (MMN) is tested and the long-term follow-up is made to record the variation of consciousness. A higher incidence rate of the MMN can be observed in MCS cases than in VS cases. In the long-term recovery, the MCS cases with MMN have more possibility of recovering to consciousness, but not the VS cases without MMN. Thus, as one of classical protocols of the event related potential(ERP), the MMN might be a method for predicting the consciousness recovery in the DOC cases, related with their prognosis.

disorder of consciousness  /  vegetative state  /  minimally conscious state  /  prognosis  /  mismatch negativity