Human phenomics research stands as the strategic high ground in the post−genomic era, and the launch of the International Human Phenome Project (IHPP) has garnered broad consensus within the global scientific community. The IHPP centers on the core scientific challenge of "delineating the associations and regulatory mechanisms between genes, phenotypes, and the environment, as well as between macro− and micro−phenotypes". Its primary objective is to establish the next−generation scientific "human phenome map" for life sciences and biomedicine. This ambitious vision has earned widespread recognition and enthusiastic support from the global scientific community. The paradigm of phenomics research is profoundly advancing the study of human health mechanisms and catalyzing a shift in healthcare models from a "disease−centric" to a "health−centric" approach. With the rapid development of precision phenotyping technologies and the deep integration with artificial intelligence, standardizing semantic identifiers, data governing, and establishing robust data−sharing ecosystems will emerge as pivotal challenges for future phenomics research.