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China's pharmaceutical industry has made remarkable progress in development, yet it also faces significant challenges in technological innovation and industrial upgrading. This paper provides a systematic overview of the technological architecture underlying synthetic biomanufacturing, highlighting its core advantages grounded in the use of renewable feedstocks, environmentally benign processes, and superior atom economy. On this basis, the paper offers an in−depth discussion of the innovative applications and recent advancements of synthetic biomanufacturing in the synthesis of chemical active pharmaceutical ingredients, bioactive constituents of modernized traditional Chinese medicine, and macromolecular therapeutics including proteins and antibodies. Despite its promising outlook, the field still faces key constraints such as suboptimal technology translation efficiency, barriers to interdisciplinary integration, and limited end−to−end process consolidation across the value chain. To overcome these limitations, it is imperative to strengthen AI−enabled enzyme engineering and metabolic pathway optimization, while promoting deeper convergence with materials science, chemical engineering, and related disciplines to establish next−generation biomanufacturing platforms. In conclusion, synthetic biomanufacturing represents both a strategic driver and an indispensable pathway for advancing China's pharmaceutical industry toward greater precision, efficiency, and intelligence, thereby reinforcing its global competitiveness.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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