Gu Fangzhou's work has significantly improved the effectiveness of polio attenuated vaccine and protected millions of children from the threat of polio. As a pioneer in the development of China's oral attenuated vaccine through cell culture, Gu's journey into public health and virology is explored in this paper. The reasons behind Gu's pursuit of a career in public health and virology are introduced and the process of developing China's first batches of attenuated polio vaccines is detailed. Furthermore, the factors influencing the choice of technical routes for polio vaccine development is discussed, as well as the processes and results of vaccine production, verification, and clinical trials. Gu has closely linked his personal destiny with the future of the nation. His research and efforts have significantly improved the health and quality of life for hundreds of millions of people.

Gu Fangzhou  /  polio  /  attenuated vaccine  /  public health  /  history of science and technology