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Research progress of anti-inflammatory drugs in osteoarthritis treatment
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Science & Technology Review | 2024, 42(11) : 66 - 74
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Science & Technology Review | 2024, 42(11): 66-74
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Research progress of anti-inflammatory drugs in osteoarthritis treatment
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MA Zhiyan1,2, HE Ziye3, LIANG Jiaming1,2, ZHAO Linlin1,2, ZHANG Yingyu2, LIU Yingying2,3, LIU Yajun2,4
Affiliations
    1. School of Public Health and Health Management, Shandong First Medical University, Ji'nan, 250117, China;
    2. Medical Science and Technology Innovation Center, Shandong First Medical University, Ji'nan 250117, China;
    3. School of Biomedical Sciences, Shandong First Medical University, Ji'nan 250117, China;
    4. National Orthopaedic Medical Center, Beijing Jishuitan Hospital, Beijing Institute of Orthopaedic Trauma, Beijing 100035, China
Published: 2024-06-13 doi: 10.3981/j.issn.1000-7857.2023.03.00411
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Osteoarthritis (OA) is the most common degenerative disease of joint, which is characterized by degeneration of articular cartilage and inflammation of articular capsule. Inflammatory reaction of articular cartilage is usually related to oxidative stress and secretion of proinflammatory cytokines in OA microenvironment. This article describes the role of inflammatory reaction in osteoarthritis and discusses the related progress in the treatment of osteoarthritis with cyclooxygenase, interleukin-1, inhibitor, prostaglandin synthetase inhibitor, and antioxidant stress drugs.
osteoarthritis  /  inflammatory reaction  /  cartilage injury  /  oxidative stress  /  anti-inflammatory drugs
MA Zhiyan, HE Ziye, LIANG Jiaming, ZHAO Linlin, ZHANG Yingyu, LIU Yingying, LIU Yajun. Research progress of anti-inflammatory drugs in osteoarthritis treatment[J]. Science & Technology Review, 2024 , 42 (11) : 66 -74 . DOI: 10.3981/j.issn.1000-7857.2023.03.00411
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Year 2024 volume 42 Issue 11
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doi: 10.3981/j.issn.1000-7857.2023.03.00411
  • Receive Date：2023-03-16
  • Online Date：2024-07-08
  • Published：2024-06-13
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  • Received：2023-03-16
  • Revised：2023-04-11
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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