Sepsis is a difficult problem in the field of acute and critical illness. The heart is the most susceptible organ in the pathogenesis of sepsis. Cardiac function injury and coagulation disorder are common complication in patients with severe sepsis. COVID-19 can cause viral sepsis, often accompanied by coagulation disorders and myocardial damage. This paper introduces the pathogenesis of traditional Chinese medicine (TCM) of sepsis and the pathophysiology of western medicine, and the significance of coagulation disorder in the formation of sepsis is analyzed. Through discussing the treatment means of traditional Chinese and western medicines it can be seen that TCM has certain advantages in infectious diseases and coagulation dysfunction, and can supplement the deficiency of western medicine treatment to a certain extent. However, further systematic studies are still needed to clarify the effectiveness of TCM treatment.

coagulopathy  /  sepsis  /  cardiac function injury  /  COVID-19