Science & Technology Review
|
2021, 39(18): 41-49
• Exclusive: Protect the mental health of children and adolescents •
Review of the genetic studies of mental disorders of children
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ZHENG Haohao, PANG Tao, CHANG Suhua
Affiliations
Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Research Units of Diagnosis and Treatment of Mood Cognitive Disorder, Chinese Academy of Medical Sciences, Beijing 100191, China
Published: 2021-09-28
doi: 10.3981/j.issn.1000-7857.2021.18.006
Outline
Children's mental disorder is a type of abnormal behavior and mental disorder in the childhood and the adolescence, with a high incidence rate, as one of the important problems all over the world. This paper reviews the genetics research progress of several common childhood mental disorders (attention deficit, hyperactivity disorder, autism, and others). Most childhood mental disorders have a high degree of heritability. Understanding the pathogenesis of childhood mental disorders from a genetic point of view, identifying the disease-related genetic loci, and further understanding the function of the genetic loci, will provide important basic data for the disease prevention, the diagnosis and the precision treatment. This paper discusses the main genetic research types and the related main results of several common childhood mental disorders, and on this basis, outlines the functional research methods and results after the identification of the genetic loci, and finally proposes some future directions for the genetic research of childhood mental disorders. The result will prouide inspiration for the future genetic research of childhood mental disorders.
children and adolescents
/
mental disorders
/
genetic mechanism
/
comorbidity
/
genetic correlation
ZHENG Haohao, PANG Tao, CHANG Suhua.
Review of the genetic studies of mental disorders of children[J].
Science & Technology Review,
2021
, 39
(18)
: 41
-49
.
DOI: 10.3981/j.issn.1000-7857.2021.18.006
Year 2021 volume 39 Issue 18
PDF
776
264
Cite this Article
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Article Info
doi: 10.3981/j.issn.1000-7857.2021.18.006
- Receive Date:2020-10-22
- Online Date:2021-10-09
- Published:2021-09-28