The oversea researches on human health and safety in space exploration have been focused on the physiological effects of weightlessness and their internal mechanisms for decades. A series of breakthroughs have been made in physiological effects and the mechanisms of diseases, including cardiovascular dysfunction, bone loss, muscle atrophy, space motion diseases, and microgravity enviroment. China's researches in this field started relatively late, however relevant researches have begn to accelerate gradually with the vigorous development of China's space exploration and manned spaceflight. Some gratifying progresses are made in some aspects such as space gravity physiology, astronaut medical supervision and medical insurance, physical and chemical regenerative environmental control and medical insurance, as well as space life science and biotechnology, which relate to space human safety and development. The special researches in molecular medicine are carried out for weightlessness bone loss. The therapeutic drugs are innovated for small nucleic acid molecules of microRNA-214, which successfully slow down the decline of osteogenic capacity and bone-loss rate caused by simulated weightlessness and aging. These breakthroughs provide important medical support for the human space exploration.

space biology  /  aeromedicine  /  aerospace gravity physiology  /  astronaut medical supervision and medical insurance  /  regenerative environmental control