Science & Technology Review
|
2019, 37(5): 72-80
• Reviews •
FOXP3+ Treg cells and immune cell therapy
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LIU Xinnan1, ZHAO Binbin1,2, CHENG Hao1, LI Bin1,2
Affiliations
1. Medicine Shanghai Institute of Immunology, Shanghai Jiao Tong University School, Shanghai 200025, China;
2. Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200025, China
Published: 2019-03-13
doi: 10.3981/j.issn.1000-7857.2019.05.010
Outline
Regulatory T(Treg) cells play a key role in the maintenance of immune homeostasis and immune tolerance. Treg cells can suppress the immune response to neoantigen and autologous antigen to control anti-tumor immunity and autoimmunity. In vitro proliferated natural or modified Treg cells can be adoptively transferred into host to promote beneficial effect or reduce side effect in different inflammatory tissue microenvironments, which may provide new approach and strategy for treating inflammatory diseases.
regulatory T cells
/
Cell modification
/
immune cell therapy
/
Car-Treg
/
FOXP3
刘鑫男, 赵彬彬, 成浩, 李斌.
FOXP3+调节性T细胞与免疫细胞治疗.
科技导报,
2019
, 37
(5)
: 72
-80
.
DOI: 10.3981/j.issn.1000-7857.2019.05.010
LIU Xinnan, ZHAO Binbin, CHENG Hao, LI Bin.
FOXP3+ Treg cells and immune cell therapy[J].
Science & Technology Review,
2019
, 37
(5)
: 72
-80
.
DOI: 10.3981/j.issn.1000-7857.2019.05.010
Year 2019 volume 37 Issue 5
PDF
772
231
Cite this Article
BibTeX
Article Info
doi: 10.3981/j.issn.1000-7857.2019.05.010
- Receive Date:2018-03-11
- Online Date:2019-04-01
- Published:2019-03-13