The diagnosis and the treatment of the severe mental disorder, represented by schizophrenia, are difficult as a clinical medicine problem. In recent years, the clinical and basic researches are focused on the prodromal psychosis, with the development of techniques and concepts in psychotic early intervention to a great extent. In this paper, the latest progress of the clinical and behavioral characteristics, the biological markers and the effective intervention for individuals at high risk of psychosis are reviewed, and the future development directions of related researches in early identification and intervention techniques for psychosis are pointed out.

prodromal psychosis  /  clinical high risk  /  ultra high risk  /  biomarker  /  early intervention