This paper identifies ten kinds of environmental pollutants with antiestrogen effects, focusing on their antagonist effects on the E₂ levels, the E₂ function and the female characters. Furthermore, the mechanism of antiestrogen effects in the synthesis, the transportation, the receptor binding and the metabolism of E₂ is discussed. Finally, based on the above analyses, the future researches of the antiestrogen effects and the underlying mechanism of environmental pollutants are suggested.

environmental pollutants  /  antiestrogen effects  /  17β-estradiol  /  estrogen receptor  /  aryl hydrocarbon receptor