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The relationship between sleep duration, cognitive function, handgrip strength,and the risk of cardiovascular diseases in middle-aged and elderly adults
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Yiming MAO1, 2, Yi ZHUANG2, Linlin ZHANG1
Chinese Nursing Research | 2026, 40(10) : 1686 - 1692
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Chinese Nursing Research | 2026, 40(10): 1686-1692
• Interdisciplinary Nursing Study •
The relationship between sleep duration, cognitive function, handgrip strength,and the risk of cardiovascular diseases in middle-aged and elderly adults
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Yiming MAO1, 2, Yi ZHUANG2, Linlin ZHANG1
Affiliations
  • 1School of Medical and Health Engineering, Changzhou University, Jiangsu 213164 China
  • 2The Third Affiliated Hospital of Nanjing Medical University/Changzhou Second People's Hospital
Published: 2026-05-25 doi: 10.12102/j.issn.1009-6493.2026.10.010
Outline
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Objective

To analyze the relationships between sleep duration,cognitive function,handgrip strength,and the risk of cardiovascular diseases(CVD) in middle-aged and elderly adults.

Methods

Based on data from the China Health and Retirement Longitudinal Study for the years 2011,2013,2015,2018,and 2020,restricted cubic spline curves were employed to investigate potential non-linear relationships between sleep duration,cognitive function,handgrip strength,and the risk of CVD.Log-Rank tests and Kaplan-Meier curves were utilized to analyze the relationships between sleep duration,cognitive function,handgrip strength,and the cumulative incidence of CVD.Cox proportional hazards models were applied to examine the associations between variables.The mediating roles of handgrip strength and cognitive function in the relationship between sleep duration and CVD risk were analyzed.

Results

A U-shaped association was observed between sleep duration and the risk of CVD.Middle-aged and elderly adults with shorter sleep duration and lower handgrip strength levels had higher risk of CVD.Cognitive function was found to influence the risk of CVD through the mediating effect of handgrip strength.

Conclusions

Middle-aged and elderly adults could potentially prevent CVD by optimizing sleep duration,enhancing muscle function and so on.

middle-aged and elderly adults  /  sleep duration  /  cognitive function  /  handgrip strength  /  cardiovascular diseases  /  correlation  /  CHARLS
毛一鸣, 庄毅, 张琳琳. 中老年人睡眠时长、认知功能、握力与心血管疾病发生风险的关系. 护理研究, 2026 , 40 (10) : 1686 -1692 . DOI: 10.12102/j.issn.1009-6493.2026.10.010
Yiming MAO, Yi ZHUANG, Linlin ZHANG. The relationship between sleep duration, cognitive function, handgrip strength,and the risk of cardiovascular diseases in middle-aged and elderly adults[J]. Chinese Nursing Research, 2026 , 40 (10) : 1686 -1692 . DOI: 10.12102/j.issn.1009-6493.2026.10.010
Appendix
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Year 2026 volume 40 Issue 10
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Article Info
doi: 10.12102/j.issn.1009-6493.2026.10.010
  • Receive Date：2025-05-30
  • Online Date：2026-10-30
  • Published：2026-05-25
Article Data
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History
  • Received：2025-05-30
  • Revised：2026-04-20
Affiliations
    1School of Medical and Health Engineering, Changzhou University, Jiangsu 213164 China
    2The Third Affiliated Hospital of Nanjing Medical University/Changzhou Second People's Hospital
References
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https://castjournals.cast.org.cn/joweb/hlyj/EN/10.12102/j.issn.1009-6493.2026.10.010
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