To explore the dose-response relationship between hypothermia risk scores and the risk of concurrent trauma-induced coagulopathy(TIC) in emergency trauma patients.

A total of 220 emergency trauma patients admitted to our hospital from April 2023 to December 2024 were selected as the study subjects.They were divided into a TIC group and a non-TIC group based on the concurrent TIC condition.Univariate and multivariate Logistic regression analyses were used to explore the influencing factors of concurrent TIC in emergency trauma patients.The impact of the hypothermia risk score on concurrent TIC was analyzed after adjusting for different covariates.Restricted cubic spline(RCS) and threshold effect analyses were employed to investigate the dose-response relationship between the hypothermia risk score and the risk of concurrent TIC.

Among the 220 emergency trauma patients,42 developed TIC,resulting in an incidence of 19.09%. The hypothermia risk scores were 24.31±8.27.The hypothermia risk score was significantly higher in the TIC group than that in the non-TIC group(P=0.012). Multivariate Logistic regression analysis showed that the hypothermia risk score and admission hemoglobin level were influencing factors of concurrent TIC in emergency trauma patients(both P<0.05).After adjusting for covariates,the hypothermia risk score remained associated with concurrent TIC in emergency trauma patients(P=0.046).The RCS curve indicated a nonlinear dose-response relationship between the hypothermia risk score and concurrent TIC after adjusting for covariates(P_{for overall}=0.002,P_{for nonlinear}=0.023).The threshold effect analysis revealed a threshold effect between the hypothermia risk score and concurrent TIC(P_{for likelihood ratio test}=0.007).When the hypothermia risk score was≥25,each one-point increased in the score was associated with a 0.170-fold increase in the risk of concurrent TIC.Subgroup analysis showed that the relationship between the hypothermia risk score and concurrent TIC was not significantly influenced by gender,age,body mass index,hypertension,diabetes,or hyperlipidemia(all P_{for interaction}>0.05).

There exists a nonlinear dose-response relationship between the hypothermia risk score and concurrent TIC in emergency trauma patients.When the hypothermia risk score is ≥25,the risk of concurrent TIC increases with higher scores.