Full
Outline
To systematically review the outcome indicators used in non-pharmacological intervention studies for elderly patients with oral frailty,so as to provide evidence-based support for developing non-pharmacological intervention protocols and their effectiveness evaluation systems for oral frailty in older adults.
A systematic search was conducted in PubMed,EMbase,Cochrane Library,SinoMed,CNKI,WanFang,and VIP databases for relevant literature,with the search period extending from database inception to December 31, 2025.Data were extracted from the included studies,with a focus on analyzing the types of outcome indicators and their corresponding measurement tools.
A total of 33 studies were included,comprising 32 English-language and 1 Chinese-language publication.Forty-two outcome indicators were extracted and categorized into 5 core domains and 19 outcome domains based on the Core Outcome Measures in Effectiveness Trials(COMET) classification framework.
There is a lack of standardized criteria for selecting outcome indicators in non-pharmacological intervention studies for elderly patients with oral frailty.It is recommended to establish a core outcome set to promote the standardization of oral frailty intervention research. Future studies should emphasize patient-centered outcome indicators and the long-term follow-up of intervention effects.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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