To analyze the underlying causes of carbapenem-resistant Klebsiella pneumoniae(CRKP) infection in intensive care unit(ICU) of a certain medical institution,and to systematically evaluate the effectiveness of the implemented control measures,so as to provide a basis for exploring effective strategies to curb the spread of CRKP infections.

On November 28,2023,4 cases of CRKP infection were detected in the neurology ICU ward of a certain medical institution,with an infection rate of 11.76%.A comprehensive review of the medical records of the patients was conducted,and standardized sampling was carried out on the frequently touched environmental surfaces in the ward.Laboratory tests and analyses of pathogenic microorganisms were also carried out.To identify potential sources of infection and transmission routes,on-site observations and evaluations were conducted on the implementation of hand hygiene by medical staff and the compliance of environmental cleaning and disinfection procedures.

The epidemiological investigation results revealed that the main cause of CRKP infection was closely related to the incomplete disinfection of environmental surfaces in the ward(especially in the frequently touched areas) and the low compliance of medical staff with hand hygiene measures.The hospital administrators promptly formulated and implemented a number of targeted strengthening control measures,and 4 patients recovered and were discharged from the hospital.No CRKP infection cases were found in the hospital.

Strictly implementing thorough disinfection of environmental surfaces and effectively improving the compliance of medical staff with hand hygiene are the key links for quickly controlling the CRKP infection in ICU.Establishing and implementing a strict hospital infection prevention and control system play a decisive role in blocking the transmission of drug-resistant bacteria.