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Outline
To construct a dynamic nomogram (DynNom) model for predicting postoperative recurrence in patients with glioma based on LASSO-logistic regression analysis.
Patients with glioma who underwent surgical treatment at The First Affiliated Hospital of Nanjing Medical University from August 2022 to December 2024 were selected as the study subjects.Their clinical data were collected.Univariate and multivariate LASSO-Logistic regression analyses were used to identify influencing factors for postoperative recurrence of glioma.A DynNom scoring model was established.
Among the 211 patients with glioma,57 experienced recurrence within 12 months after surgery,resulting in a recurrence rate of 27.01%.Regression analysis showed that Karnofsky Performance Status(KPS) score,disease stage,maximum tumor diameter,surgical resection,and postoperative concurrent chemoradiotherapy were influencing factors for postoperative recurrence in patients with glioma(P<0.05).The DynNom scoring model,established based on the regression analysis results,had an area under the receiver operating characteristic(ROC) curve(AUC) of 0.807.The calibration curve was close to the ideal curve.
Multiple factors influence postoperative recurrence in patients with glioma.The DynNom scoring model constructed based on these risk factors demonstrates good predictive performance for the risk of postoperative recurrence in patients with glioma.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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