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Longitudinal trajectories and influencing factors of activation in chronic heart failure patients based on latent class growth model
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Min CHEN, Xian YUAN, Juan GENG
Chinese Nursing Research | 2026, 40(13) : 2278 - 2286
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Chinese Nursing Research | 2026, 40(13): 2278-2286
• Original Articles •
Longitudinal trajectories and influencing factors of activation in chronic heart failure patients based on latent class growth model
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Min CHEN, Xian YUAN, Juan GENG
Affiliations
  • 1The Affiliated Huai'an Hospital of Xuzhou Medical University/Huai'an Second People's Hospital, Jiangsu 223000 China
Published: 2026-07-10 doi: 10.12102/j.issn.1009-6493.2026.13.012
Outline
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Objective

To explore the potential categories of longitudinal trajectories of patient activation in individuals with chronic heart failure and to analyze their influencing factors.

Methods

Patients with chronic heart failure admitted to our hospital from January 2023 to August 2024 were selected as the study subjects.Before discharge(T1),surveys were conducted using a general information questionnaire,the Chinese version of the Patient Activation Measure(PAM13),the FRAIL scale(to screen for frailty risk),and the Social Support Rating Scale(SSRS).Patient activation was reassessed using the Chinese version of the PAM 13 at 1 month(T2),3 months(T3),and 6 months(T4) after discharge.Spearman correlation analysis was used to examine the correlations of patient activation scores across the four time points.Latent class growth modeling was employed to identify potential categories of patient activation trajectories,and multinomial logistic regression was performed to analyze the influencing factors of these trajectory categories.

Results

A total of 216 patients completed the study.The patient activation scores at T1,T2,T3,and T4 were 54.6 (40.1,66.0),56.4(43.4,73.1),51.4(41.7,63.2),and 51.4(42.1,66.0),respectively.Spearman correlation analysis showed positive correlations among patient activation scores at all four time points(all P<0.01).The latent class growth model identified three distinct trajectory categories:high activation-stable group(27.3%),moderate activation-declining group(32.9%),and low activation-gradually increasing group(39.8%).Multinomial Logistic regression revealed that education level,NYHA functional class,comorbidities,frailty status,and social support were significant influencing factors for the trajectory categories of patient activation in chronic heart failure patients(all P<0.05).

Conclusions

There is significant inter-individual heterogeneity in the trajectories of patient activation among chronic heart failure patients,which are influenced by education level,NYHA functional class,comorbidities,frailty status,and social support.Healthcare providers should implement targeted interventions based on the characteristics of patients' activation trajectories to comprehensively improve their activation levels.

chronic heart failure  /  patient activation  /  trajectory  /  latent class growth model  /  influencing factors  /  longitudinal study
陈敏, 袁娴, 耿娟. 基于潜类别增长模型的慢性心力衰竭病人积极度纵向轨迹及影响因素. 护理研究, 2026 , 40 (13) : 2278 -2286 . DOI: 10.12102/j.issn.1009-6493.2026.13.012
Min CHEN, Xian YUAN, Juan GENG. Longitudinal trajectories and influencing factors of activation in chronic heart failure patients based on latent class growth model[J]. Chinese Nursing Research, 2026 , 40 (13) : 2278 -2286 . DOI: 10.12102/j.issn.1009-6493.2026.13.012
Year 2026 volume 40 Issue 13
37
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doi: 10.12102/j.issn.1009-6493.2026.13.012
  • Receive Date:2025-07-04
  • Online Date:2026-10-30
  • Published:2026-07-10
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History
  • Received:2025-07-04
  • Revised:2026-05-17
Affiliations
    1The Affiliated Huai'an Hospital of Xuzhou Medical University/Huai'an Second People's Hospital, Jiangsu 223000 China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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