Full
Outline
To observe the effectiveness of a family nurse dietary therapy regimen,developed based on the family nurse dietary therapy theory,in improving the severity of menopausal symptoms,metabolic indicators,and oxidative stress levels in overweight and obese patients with perimenopausal syndrome.
A total of 70 overweight and obese patients with perimenopausal syndrome were selected as study subjects from the gynecology outpatient clinic of a tertiary grade A hospital and a resident community in Shanxi province from May 25,2025 to August 29,2025.Patients were randomly divided into control group and intervention group,35 cases each.The control group patients received a conventional dietary program,while the intervention group cases received the family nurse dietary therapy regimen in addition to routine care.Anthropometric indicators,blood biochemical indicators,inflammatory indicators,and oxidative stress indicators were evaluated before the intervention and 6 weeks after the intervention.
During the intervention period,8 cases dropped out,31 patients in each group completed the trial.After 6 weeks of intervention,the intervention group demonstrated significantly lower levels than those before the intervention in terms of body weight,body mass index(BMI),waist circumference,abdominal circumference,hip circumference,body fat mass,visceral fat area,fasting plasma glucose(FPG),fasting insulin(FINS),homeostatic model assessment for insulin resistance(HOMA-IR),total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),homocysteine(Hcy),alanine aminotransferase(ALT),aspartate aminotransferase(AST),blood urea nitrogen(BUN),serum creatinine(Scr),serum uric acid(UA),tumor necrosis factor-alpha(TNF-α),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),and malondialdehyde(MDA).Furthermore,the BMI,abdominal circumference,hip circumference,body fat mass,FPG,HOMA-IR,TG,LDL-C,Hcy,TNF-α,hs-CRP,IL-6,and MDA were significantly lower in the intervention group than that in the control group at the same time.Superoxide dismutase(SOD) levels were higher in the intervention group than that before the intervention.The SOD was significantly higher in the intervention group that in the control group at the same time(P<0.05).
The family nurse dietary therapy regimen,rich in non-nutrients,alleviated menopausal symptoms and effectively improved body composition,glucose and lipid metabolism,and inflammatory and oxidative stress levels in overweight and obese patients with perimenopausal syndrome.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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