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Relationship between the classification of the estimated cardiorespiratory fitness change trajectories and the risk of cardiovascular disease among middle-aged and older adults in China
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Yanyan LIANG, Yuhong SU, Zhihao WEN, Jianli HUANG, Qijuan CHEN
Chinese Nursing Research | 2026, 40(14) : 2404 - 2413
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Chinese Nursing Research | 2026, 40(14): 2404-2413
• Original Articles •
Relationship between the classification of the estimated cardiorespiratory fitness change trajectories and the risk of cardiovascular disease among middle-aged and older adults in China
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Yanyan LIANG, Yuhong SU, Zhihao WEN, Jianli HUANG, Qijuan CHEN
Affiliations
  • 1The First Affiliated Hospital of Guangxi University of Chinese Medicine, Guangxi 530023 China
Published: 2026-07-25 doi: 10.12102/j.issn.1009-6493.2026.14.003
Outline
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Objective

To explore the change trajectories of estimated cardiorespiratory fitness(eCRF) among middle-aged and older adults in China based on data from the China Health and Retirement Longitudinal Study(CHARLS) and to analyze the relationship betweent different classification of the trajectories and the risk of cardiovascular disease.

Methods

Data from 4 172 middle-aged and older adults who completed follow-up in CHARLS from 2011 to 2020 were included.eCRF levels in 2011,2013,and 2015 were calculated using non-exercise equations.Group-based trajectory modeling was employed to identify the classification of the eCRF change trajectories.Logistic regression was used to analyze the relationship between the classification of the eCRF change trajectories and the risk of cardiovascular disease,followed by subgroup analyses.

Results

Among the 4 172 participants,1 150 developed cardiovascular disease,yielding an incidence rate of 27.6%.Three distinct eCRF change trajectories were identified,namely low-increasing then decreasing group(7.5%),moderate-rapidly decreasing group(28.0%),and high-slowly decreasing group(64.5%).After adjusting for multiple variables,Logistic regression showed that compared with the high-slowly decreasing group,both the low-increasing then decreasing group(OR=1.90,95%CI 1.43-2.51) and the moderate-rapidly decreasing group(OR=1.42,95%CI 1.20-1.69) had a higher risk of cardiovascular disease.Subgroup analyses revealed an interaction between the classification of the eCRF change trajectories and hypertension(P=0.008).

Conclusions

Group heterogeneity exists in eCRF change trajectories among middle-aged and older adults in China.Those with higher eCRF levels tend to have a lower risk of cardiovascular disease.Hypertensive status may influence the relative strength of the association between the classification of the eCRF change trajectories and the risk of cardiovascular disease.

estimated cardiorespiratory fitness  /  cardiovascular disease  /  group-based trajectory modeling  /  cohort study
梁燕燕, 苏宇虹, 温志浩, 黄俭丽, 陈启娟. 我国中老年人估算心肺适能水平变化轨迹类别与心血管疾病发生风险的关系. 护理研究, 2026 , 40 (14) : 2404 -2413 . DOI: 10.12102/j.issn.1009-6493.2026.14.003
Yanyan LIANG, Yuhong SU, Zhihao WEN, Jianli HUANG, Qijuan CHEN. Relationship between the classification of the estimated cardiorespiratory fitness change trajectories and the risk of cardiovascular disease among middle-aged and older adults in China[J]. Chinese Nursing Research, 2026 , 40 (14) : 2404 -2413 . DOI: 10.12102/j.issn.1009-6493.2026.14.003
Year 2026 volume 40 Issue 14
31
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doi: 10.12102/j.issn.1009-6493.2026.14.003
  • Receive Date:2025-09-23
  • Online Date:2026-10-30
  • Published:2026-07-25
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History
  • Received:2025-09-23
  • Revised:2026-06-11
Affiliations
    1The First Affiliated Hospital of Guangxi University of Chinese Medicine, Guangxi 530023 China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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