Full
Outline
To investigate the incidence and influencing factors of lower extremity deep vein thrombosis(DVT) after intracranial mechanical thrombectomy in patients with acute ischemic stroke(AIS),and to construct a risk prediction model.
A total of 315 patients admitted to the neurointensive care unit of Nanfang Hospital Southern Medical University were enrolled as study subjects from January 2023 to September 2024. Univariate and multivariate Logistic regression analyses were performed to explore the influencing factors for DVT.A Nomogram prediction model was constructed.The prediction model was evaluated using the receiver operating characteristic(ROC) curve,Hosmer-Lemeshow test,calibration curve,and clinical decision curve analysis(DCA).
The incidence of lower extremity DVT after mechanical thrombectomy in the 315 AIS patients was 28.89%(91/315).Logistic regression analysis showed that age,National Institute of Health Stroke Scale(NIHSS) score,D-dimer level,puncture time,and operation time were influencing factors for lower extremity DVT after mechanical thrombectomy in AIS patients(all P<0.05).A Nomogram model was constructed based on these influencing factors.The area under the ROC curve was 0.916(95% CI 0.883-0.949).The Youden index was 0.675.The sensitivity was 0.912.The specificity was 0.763.The Bootstrap test indicated good model calibration.Clinical DCA demonstrated good clinical applicability within the threshold probability range of 0.01-0.90.
Age,NIHSS score,D-dimer level,puncture time,and operation time were identified as factors affecting the occurrence of lower extremity DVT after mechanical thrombectomy in AIS patients.The Nomogram model constructed based on influencing factors demonstrated good predictive performance and may serve as a quantitative tool for nurses to identify high-risk patients at an early stage.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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