To investigate the application effect of outpatient short-term automatic thought recognition training in patients with comorbid anxiety and depression,and to provide references for optimizing outpatient treatment strategies.
A total of 82 patients with comorbid anxiety and depression were divided into an automatic thought training combined with pharmacotherapy group(combined treatment group,37 cases) and a pharmacotherapy alone group(medication alone group,45 cases).The Hamilton Anxiety Scale(HAMA) and Hamilton Depression Scale(HAMD) were used as primary outcome measures.A linear mixed-effects model was used to compare symptom changes between the two groups from the first outpatient visit to the last outpatient visit.
The linear mixed-effects model showed a statistically significant group-by-time interaction effect for HAMD total scores between the two groups(P<0.001).The combined treatment group showed greater changes in depression total scores at the end of 4 weeks and 8 weeks of treatment compared with the medication alone group(P<0.05).The combined treatment group also showed greater changes in anxiety total scores at the end of 8 weeks compared with the medication alone group(P=0.02).
In patients with comorbid anxiety and depression,combined automatic thought training demonstrates better clinical efficacy in symptom improvement compared with pharmacotherapy alone.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |