To systematically evaluate the risk factors for the occurrence of colorectal polyps.
A computerized search was conducted in CNKI,VIP,WanFang Database,CBM,PubMed,Cochrane Library,and EMbase Database for studies on the risk factors of colorectal polyps.The search period spanned from the establishment of the databases to June 2,2025.Two researchers independently performed literature screening,quality assessment,and data extraction.Meta-analysis was conducted using Review Manager 5.4 software,and Egger's test was performed using Stata 18.0 software.
A total of 29 studies were included,involving 9 987 patients.The results of the meta-analysis showed that age[OR=1.08,95%CI(1.06,1.11)],male[OR=1.63,95%CI(1.43,1.85)],smoking[OR=1.93,95%CI(1.68,2.21)],alcohol consumption[OR=1.58,95%CI(1.36,1.83)],abnormal triglycerides[OR=1.65,95%CI(1.43,1.90)],obesity[OR=1.67,95%CI(1.31,2.12)],fatty liver[OR=2.87,95%CI(1.87,4.40)],diabetes[OR=3.34,95%CI(2.10,5.31)],high-fat diet[OR=3.27,95%CI(2.24,4.78)],helicobacter pylori infection[OR=1.71,95%CI(1.38,2.13)],abnormal uric acid[OR=1.57,95%CI(1.22,2.03)],gallbladder disease[OR=1.78,95%CI(1.43,2.23)],family history of cancer[OR=2.43,95%CI(1.61,3.68)],abnormal cholesterol[OR=1.92,95%CI(1.39,2.65)],waist circumference[OR=1.71,95%CI(1.04,2.80)],hyperlipidemia[OR=1.54,95%CI(1.23,1.93)],and family history of polyps[OR=8.27,95%CI(2.22,30.86)] were risk factors for the occurrence of colorectal polyps.
There are many risk factors for colorectal polyps.Medical staff should enhance awareness of disease screening and provide personalized and precise intervention through a multidisciplinary integration model,reduce the incidence of precancerous polyps and alleviate the disease burden.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |