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Latent profile analysis and influencing factors of cancer-related cognitive impairment in lung cancer patients
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Xiaoju ZHU1, 2, Sixiong LUO1, 3, Haiwei FU1, Wei GUAN2, Zonghua WANG1
Chinese Nursing Research | 2026, 40(9) : 1488 - 1494
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Chinese Nursing Research | 2026, 40(9): 1488-1494
• Original Articles •
Latent profile analysis and influencing factors of cancer-related cognitive impairment in lung cancer patients
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Xiaoju ZHU1, 2, Sixiong LUO1, 3, Haiwei FU1, Wei GUAN2, Zonghua WANG1
Affiliations
  • 1Army Medical University of Chinese PLA, Chongqing 400038 China
  • 2Daping Hospital, Army Medical University of Chinese PLA
  • 3Chongqing Nursing School
Published: 2026-05-10 doi: 10.12102/j.issn.1009-6493.2026.09.008
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Objective

To explore the latent profiles of cognitive function in lung cancer patients and their influencing factors.

Methods

A total of 296 lung cancer patients who visited the oncology department of a tertiary grade A hospital in Chongqing from January to August 2025 were selected as the survey subjects.General information questionnaire,Functional Assessment of Cancer Therapy-Cognitive Function Scale,Exercise Adherence Scale,and Self-Rating Anxiety Scale were used for investigation.Latent profile analysis was employed to explore the latent profiles of cancer-related cognitive impairment,while univariate analysis and multinomial Logistic regression analysis were used to investigate the influencing factors of latent profiles in cancer-related cognitive impairment patients.

Results

Cancer-related cognitive impairment patients could be classified into three latent profiles:high cognitive function group(67.2%),moderate cognitive function group(22.6%),and low cognitive function group(10.1%).Multinomial Logistic regression results showed that educational level,tumor stage,age,exercise adherence,and anxiety were influencing factors of latent profiles of cognitive function in lung cancer patients(all P<0.05).

Conclusions

Cancer-related cognitive function in lung cancer patients exhibits group heterogeneity.It suggests that healthcare professionals should develop more targeted intervention measures based on the influencing factors of different categories of lung cancer patients' cognitive function levels.

lung cancer  /  cognitive function  /  cancer-related cognitive impairment  /  latent profile analysis  /  influencing factors  /  oncology nursing
朱晓菊, 罗思熊, 付海炜, 关伟, 王宗华. 肺癌病人癌症相关认知障碍潜在剖面分析及影响因素. 护理研究, 2026 , 40 (9) : 1488 -1494 . DOI: 10.12102/j.issn.1009-6493.2026.09.008
Xiaoju ZHU, Sixiong LUO, Haiwei FU, Wei GUAN, Zonghua WANG. Latent profile analysis and influencing factors of cancer-related cognitive impairment in lung cancer patients[J]. Chinese Nursing Research, 2026 , 40 (9) : 1488 -1494 . DOI: 10.12102/j.issn.1009-6493.2026.09.008
Year 2026 volume 40 Issue 9
58
17
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Article Info
doi: 10.12102/j.issn.1009-6493.2026.09.008
  • Receive Date:2025-12-11
  • Online Date:2026-10-28
  • Published:2026-05-10
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History
  • Received:2025-12-11
  • Revised:2026-03-19
Affiliations
    1Army Medical University of Chinese PLA, Chongqing 400038 China
    2Daping Hospital, Army Medical University of Chinese PLA
    3Chongqing Nursing School
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表12种不同金属材料的力学参数
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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