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Behavioral and psychological factors influencing adherence to adjuvant endocrine therapy in patients with breast cancer: a systematic review
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Yipei CHEN1, Heng YANG1, An'gang TONG1, 2, Ping GAO2, Lingling TANG2, Xin PENG2
Chinese Nursing Research | 2026, 40(2) : 236 - 250
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Chinese Nursing Research | 2026, 40(2): 236-250
• Interdisciplinary Nursing Study •
Behavioral and psychological factors influencing adherence to adjuvant endocrine therapy in patients with breast cancer: a systematic review
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Yipei CHEN1, Heng YANG1, An'gang TONG1, 2, Ping GAO2, Lingling TANG2, Xin PENG2
Affiliations
  • 1School of Nursing, Tongji Medical College of Huazhong University of Science and Technology, Hubei 430030 China
  • 2Union Hospital of Tongji Medical College of Huazhong University of Science and Technology
Published: 2026-01-25 doi: 10.12102/j.issn.1009-6493.2026.02.009
Outline
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Objective

To systematically review the behavioral and psychological factors influencing adherence to adjuvant endocrine therapy(AET) in patients with breast cancer,based on the theoretical domains framework.

Methods

Chinese and English literature on the behavioral and psychological factors influencing adherence to AET in patients with breast cancer was retrieved from nine databases,namely PubMed,Web of Science,EMbase,CINAHL,Cochrane Library,CBM,CNKI,WanFang Data,and VIP.Literature was independently screened by two researchers.Data was extracted.Data analysis was performed using Nvivo 14 software.Texts related to behavioral and psychological factors influencing adherence to AET were coded using the 14 domains of the theoretical domains framework as primary nodes.Secondary nodes were refined using thematic analysis.

Results

A total of 50 articles were included,yielding 297 coding references.These were synthesized into 30 secondary nodes and distributed across 12 domains of the theoretical domains framework.Environmental context and resources,emotion,and social influences were the three domains with the highest number of coding references.Physical condition was the most frequently cited factor influencing patient adherence.

Conclusions

The behavioral and psychological factors influencing adherence to AET in patients with breast cancer span multiple domains of the theoretical domains framework.These factors may interact.Future research should explore the pathways through which various factors influence adherence to enable more precise and effective behavioral interventions.

breast cancer  /  adjuvant endocrine therapy  /  adherence  /  behavioral psychology  /  theoretical domains framework  /  systematic review
陈义佩, 杨恒, 童安港, 高萍, 汤玲玲, 彭昕. 乳腺癌病人辅助内分泌治疗依从性行为心理学影响因素的系统综述. 护理研究, 2026 , 40 (2) : 236 -250 . DOI: 10.12102/j.issn.1009-6493.2026.02.009
Yipei CHEN, Heng YANG, An'gang TONG, Ping GAO, Lingling TANG, Xin PENG. Behavioral and psychological factors influencing adherence to adjuvant endocrine therapy in patients with breast cancer: a systematic review[J]. Chinese Nursing Research, 2026 , 40 (2) : 236 -250 . DOI: 10.12102/j.issn.1009-6493.2026.02.009
Year 2026 volume 40 Issue 2
44
14
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Article Info
doi: 10.12102/j.issn.1009-6493.2026.02.009
  • Receive Date:2025-02-28
  • Online Date:2026-10-28
  • Published:2026-01-25
Article Data
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History
  • Received:2025-02-28
  • Revised:2025-12-24
Affiliations
    1School of Nursing, Tongji Medical College of Huazhong University of Science and Technology, Hubei 430030 China
    2Union Hospital of Tongji Medical College of Huazhong University of Science and Technology

Corresponding:

PENG Xin, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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