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Categories of health-related quality of life and their influencing factors in patients with pulmonary arterial hypertension
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Ying JIANG1, Sijing PENG2, Xiaofeng KANG3, Min DOU1
Chinese Nursing Research | 2026, 40(14) : 2467 - 2474
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Chinese Nursing Research | 2026, 40(14): 2467-2474
• Original Articles •
Categories of health-related quality of life and their influencing factors in patients with pulmonary arterial hypertension
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Ying JIANG1, Sijing PENG2, Xiaofeng KANG3, Min DOU1
Affiliations
  • 1The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China/Anhui Provincial Hospital, Anhui 230001 China
  • 2School of Nursing, Anhui University of Chinese Medicine
  • 3School of Nursing, Peking Union Medical College
Published: 2026-07-25 doi: 10.12102/j.issn.1009-6493.2026.14.011
Outline
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Objective

To explore the categories of health-related quality of life(HRQoL) in patients with pulmonary arterial hypertension(PAH) and to analyze their influencing factors.

Methods

A total of 152 PAH patients who attended the outpatient clinic of a tertiary hospital in Beijing city were selected as the survey subjects by convenience sampling method from February to September 2022.The survey was conducted using a general information questionnaire,the Comprehensive Score for Financial Toxicity Functional Assessment of Chronic Illness Therapy(COST),the Tilburg Frailty Scale,the Hospital Anxiety and Depression Scale(HADS),and the PAH-specific HRQoL scale(EmPHasis-10).Mplus 8.3 software was used for latent profile analysis.Unordered multinomial Logistic regression analysis was used to explore the influencing factors.

Results

The total EmPHasis-10 score of PAH patients was 23.09±12.61.Their HRQoL was classified into three categories,namely good function group(28.29%),moderate limitation group(38.82%),and severe limitation group(32.89%).The regression analysis results showed that the 6-minute walk distance(6MWD),pulmonary artery systolic pressure,age,COST score,Tilburg Frailty Scale score,and HADS anxiety subscale score were the influencing factors for the HRQoL categories in PAH patients(P<0.05).

Conclusions

The HRQoL of PAH patients exhibits group heterogeneity.Nursing staff should develop individualized interventions based on the influencing factors of different HRQoL categories to improve patients' functional status and quality of life.

pulmonary arterial hypertension  /  health-related quality of life  /  latent profile analysis  /  influencing factors
江莹, 彭思敬, 康晓凤, 窦敏. 肺动脉高压病人健康相关生活质量类别及其影响因素. 护理研究, 2026 , 40 (14) : 2467 -2474 . DOI: 10.12102/j.issn.1009-6493.2026.14.011
Ying JIANG, Sijing PENG, Xiaofeng KANG, Min DOU. Categories of health-related quality of life and their influencing factors in patients with pulmonary arterial hypertension[J]. Chinese Nursing Research, 2026 , 40 (14) : 2467 -2474 . DOI: 10.12102/j.issn.1009-6493.2026.14.011
Year 2026 volume 40 Issue 14
43
18
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Article Info
doi: 10.12102/j.issn.1009-6493.2026.14.011
  • Receive Date:2025-10-24
  • Online Date:2026-10-30
  • Published:2026-07-25
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History
  • Received:2025-10-24
  • Revised:2026-04-20
Affiliations
    1The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China/Anhui Provincial Hospital, Anhui 230001 China
    2School of Nursing, Anhui University of Chinese Medicine
    3School of Nursing, Peking Union Medical College
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表12种不同金属材料的力学参数
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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