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To perform modified Shengma Biejia Decoction combined with Tiaoshen acupuncture therapy for patients with herpes zoster (HZ), and analyze the influence on pain and inflammatory factors.
According to the random number table method, 98 patients with HZ admitted to the hospital from January 2022 to January 2025 were divided into control group (n = 49, Tiaoshen acupuncture method) and combined group (n = 49, modified Shengma Biejia Decoction combined with Tiaoshen acupuncture therapy). The clinical efficacy, pain status [visual analogue scale (VAS)], serum pain mediators [neurotensin (NT), β-endorphin (β-EP), substance P (SP)], serum inflammatory factors [interleukin-2 (IL-2), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)] and occurrence of adverse reactions were compared between groups of patients.
Compared with the control group, the combined group had higher total effective rate of treatment (P <0.05). The VAS scores in the combined group after 7 days and 14 days of treatment were lower (P < 0.05), and the levels of serum NT and β-EP were higher (P <0.05) while the level of serum SP was lower (P < 0.05). The combined group had higher IL-2 (P < 0.05), lower levels of IL-6 and TNF-α (P <0.05) and lower total incidence rate of adverse reactions (P < 0.05).
The combination of modified Shengma Biejia Decoction and Tiaoshen acupuncture therapy is effective in the treatment of HZ, and it can effectively relieve the pain, and regulate the levels of pain-related mediators and inflammatory factors, with few adverse reactions.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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