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Research Progress on the Regulation of MAPK Signaling Pathway by Traditional Chinese Medicine in the Treatment of Endometriosis
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Zhen ZHAO1, Fangyuan LIU2, Fengjuan HAN2, *
Acta Chinese Medicine and Pharmacology | 2026, 54(5) : 114 - 120
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Acta Chinese Medicine and Pharmacology | 2026, 54(5): 114-120
Research Progress on the Regulation of MAPK Signaling Pathway by Traditional Chinese Medicine in the Treatment of Endometriosis
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Zhen ZHAO1, Fangyuan LIU2, Fengjuan HAN2, *
Affiliations
  • 1.Heilongjiang University of Chinese Medicine, Harbin 150040, China
  • 2.The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China
Published: 2026-05-20 doi: 10.19664/j.cnki.1002-2392.260108
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Endometriosis (EMs) is a chronic inflammatory and estrogen-dependent disease with obvious adverse reactions and a high recurrence rate in clinical treatment. The MAPK signaling pathway plays an important role in the occurrence and development of EMs. Studies have shown that traditional Chinese medicine exhibits the characteristics of multiple targets and multiple mechanisms in the treatment of EMs. It can exert an anti-EMs effect by regulating the MAPK signaling pathway, inhibiting the production of inflammatory factors, promoting cell apoptosis, suppressing abnormal proliferation, migration and invasion of EMs, and inhibiting pathological angiogenesis. This article explored the mechanism of action of active ingredients of traditional Chinese medicine and compound and patent traditional Chinese medicine in treating EMs by regulating the MAPK signaling pathway, with the aim of providing a certain theoretical basis for the prevention and treatment of EMs with traditional Chinese medicine.

Endometriosis  /  MAPK signal pathway  /  Traditional Chinese medicine  /  Research progress
Zhen ZHAO, Fangyuan LIU, Fengjuan HAN. Research Progress on the Regulation of MAPK Signaling Pathway by Traditional Chinese Medicine in the Treatment of Endometriosis[J]. Acta Chinese Medicine and Pharmacology, 2026 , 54 (5) : 114 -120 . DOI: 10.19664/j.cnki.1002-2392.260108
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Article Info
doi: 10.19664/j.cnki.1002-2392.260108
  • Receive Date：2025-08-04
  • Online Date：2026-09-17
  • Published：2026-05-20
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History
  • Received：2025-08-04
  • Revised：2025-12-30
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Affiliations
    1.Heilongjiang University of Chinese Medicine, Harbin 150040, China
    2.The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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