Objective: To analyze the effect of modified Banxia Xiexin Decoction in treating functional dyspepsia (FD).Methods: A total of 100 FD patients treated in the outpatient department of Jiangyin Traditional Chinese Medicine Hospital from January 2024 to December 2024 were retrospectively included as study subjects. The patients were randomly divided into a control group and an observation group, with 50 cases in each group. Case data were sourced from the hospital's electronic medical record system. The control group received conventional Western medicine treatment, while the observation group received conventional Western medicine combined with modified Banxia Xiexin Decoction. After 4 weeks of treatment, the efficacy of the two groups was compared. Before treatment, at week 1, and at week 4 of treatment, Traditional Chinese Medicine syndrome scores (epigastric fullness, reduced appetite, fatigue), gastric antrum contraction frequency, gastric antrum contraction amplitude, gastric half - emptying time, motilin, gastrin, and somatostatin (SS) were compared between the two groups. Adverse reactions in both groups were also recorded.Results: After 4 weeks of treatment, the total effective rate in the observation group was higher than that in the control group (P < 0.05) ; before treatment, at 1 week, and at 4 weeks of treatment, scores of traditional Chinese medicine (TCM) syndromes such as epigastric and abdominal fullness, reduced appetite, and fatigue, as well as antral contraction amplitude, gastric half - emptying time, and SS showed a gradual decreasing trend (P < 0.05), with the observation group lower than the control group (P <0.05). Antral contraction frequency, motilin, and gastrin showed a gradual increasing trend (P < 0.05), with the observation group higher than the control group. The main effects between groups were significant (P <0.05).Conclusion: modified Banxia Xiexin Decoction with significantly effective in treating functional dyspepsia (FD) can effectively improve patients' gastrointestinal motility and gastrointestinal hormone levels, and relieve clinical symptoms.

Functional dyspepsia  /  Banxia Xiexin Decoction  /  Gastric motility  /  Gastrointestinal hormones