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Outline
Objective:To observe the clinical efficacy of small needle-knife combined with ozone water in the treatment of patients with gout stones.Methods:84 gout patients were randomly divided into an observation group and a control group，with 42 cases in each group.The control group received conventional treatment，while the observation group received a combination of small needle knife and ozone water external therapy in addition to the treatment given to the control gr-oup. Both groups were treated for 3 weeks. Blood uric acid levels，dual-source CT gout stone volume，visual analogue scale（VAS）scores，and traditional Chinese medicine（TCM）syndrome scores were compared after treatment.Results:After treatment，blood uric acid levels，VAS scores，and TCMsyndrome scores in both groups were significantly lower than those before treatment（P＜0.01），and the observation group showed lower blood uric acid levels，VAS scores，and TCMsyndrome scores compared to the control group（P＜0.05）.After treatment，dual-source CT showed that the gout stone volume in the observation group was significantly reduced（P＜0.01），which was also significantly smaller than that of the control group at the same time point（P＜0.01）.The effective rate in the observation group was 95.24%，compared to 76.19% in the control group，with the observation group showing a significantly higher effective rate（P＜0.01）. Conclusion:External treatment with small needle-knife combined with ozone water can significantly reduce the size of gout stones in patients，alleviate clinical symptoms，improve quality of life and demonstrate high clinical efficacy and safety.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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