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Recent Advances in Research on the Effects of Aminobutyric Acid on Sleep
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Liuyan ZHU1, 2, Dan YAO1, 2, *
Chinese Pharmaceutical Journal | 2025, 60(5) : 441 - 446
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Chinese Pharmaceutical Journal | 2025, 60(5): 441-446
Recent Advances in Research on the Effects of Aminobutyric Acid on Sleep
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Liuyan ZHU1, 2, Dan YAO1, 2, *
Affiliations
  • 1 Department of Pediatric Health Care, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
  • 2 National Clinical Research Center for Child Health, Hangzhou 310003, China
Published: 2025-03-08 doi: 10.11669/cpj.2025.05.001
Outline
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Sleep disorders are increasingly prevalent within the population, and optimal sleep is essential for overall health. The sleep-wake cycle is a multifaceted process influenced by a variety of factors, including several neurotransmitters such as acetylcholine, norepinephrine, serotonin, histamine, dopamine, orexin, and gamma-aminobutyric acid (GABA). The activity of these neurotransmitters is further modulated by numerous nutrients involved in their metabolic pathways. In recent years, GABA has garnered significant attention due to its critical role in sleep regulation. This review aims to examine the mechanisms through which GABA affects sleep, its clinical implications, as well as recent advancements in research and future directions in this field.

aminobutyric acid  /  sleep problem  /  biological rhythm
Liuyan ZHU, Dan YAO. Recent Advances in Research on the Effects of Aminobutyric Acid on Sleep[J]. Chinese Pharmaceutical Journal, 2025 , 60 (5) : 441 -446 . DOI: 10.11669/cpj.2025.05.001
Year 2025 volume 60 Issue 5
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doi: 10.11669/cpj.2025.05.001
  • Receive Date:2024-08-13
  • Online Date:2025-11-07
  • Published:2025-03-08
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  • Received:2024-08-13
Affiliations
    1 Department of Pediatric Health Care, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
    2 National Clinical Research Center for Child Health, Hangzhou 310003, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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