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Epidemic characteristics and spatial-temporal clustering of hepatitis B in children aged under 15 years in Guangxi Zhuang Autonomous Region, 2009–2023
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Huandong WANG1, Ying HUANG2, 3, Weiwen ZHOU2, 3, Jing LIU2, 3, Yanning LI1, Sha LI2, 3
Chinese Journal of Public Health | 2025, 41(8) : 954 - 960
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Chinese Journal of Public Health | 2025, 41(8): 954-960
• Special Report – Prevention as the First Line of Defense Against Hepatitis B •
Epidemic characteristics and spatial-temporal clustering of hepatitis B in children aged under 15 years in Guangxi Zhuang Autonomous Region, 2009–2023
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Huandong WANG1, Ying HUANG2, 3, Weiwen ZHOU2, 3, Jing LIU2, 3, Yanning LI1, Sha LI2, 3
Affiliations
  • 1School of Public Health, Guangxi Medical University, Nanning 530021, China
  • 2Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China
  • 3Guangxi Key Laboratory for the Prevention and Control of Viral Hepatitis, Nanning 530028, China
Published: 2025-08-10 doi: 10.11847/zgggws1147558
Outline
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Objective

To analyze the epidemiological characteristics, spatial-temporal clustering, and change trend of hepatitis B among children aged under 15 years in Guangxi Zhuang Autonomous Region from 2009 to 2023.

Methods

The research data were collected from the China Information System of Disease Control and Prevention. The descriptive analysis, spatial autocorrelation analysis, and spatio-temporal scanning analysis were performed to explore the spatio-temporal distribution characteristics and clustering pattern of hepatitis B in children aged under 15 years in Guangxi Zhuang Autonomous Region.

Results

From 2009 to 2023, the reported incidence of hepatitis B in children aged under 15 years in Guangxi Zhuang Autonomous Region showed a downward trend. The sex ratio of male to female incidence was 1.77∶1. The average annual incidence was the highest (6.35/100 000) in the age group of 10 to <15 years. Spatial autocorrelation analysis showed that there was significant spatial clustering in the incidence of hepatitis B among children in Guangxi Zhuang Autonomous Region. High-high clustering was mainly concentrated in western Guangxi Zhuang Autonomous Region and some central regions, while low-low clustering was concentrated in northeastern Guangxi Zhuang Autonomous Region. Spatiotemporal scanning analysis detected 2 high-incidence clusters and 1 low-incidence cluster.

Conclusions

The prevention and control of hepatitis B in children in Guangxi Zhuang Autonomous Region has achieved remarkable results, while there is still a phenomenon of spatial-temporal clustering. In high-incidence areas, it is necessary to strengthen strategies such as vaccination, mother-to-child blocking, and health education. In low-incidence areas, existing prevention and control measures should be kept to consolidate the reduction in the incidence of hepatitis B in children.

hepatitis B in children  /  epidemic characteristic  /  spatial-temporal clustering  /  Guangxi Zhuang Autonomous Region
王焕东, 黄影, 周为文, 刘静, 黎燕宁, 黎沙. 2009—2023年广西壮族自治区15岁以下儿童乙肝流行特征及时空聚集性分析. 中国公共卫生, 2025 , 41 (8) : 954 -960 . DOI: 10.11847/zgggws1147558
Huandong WANG, Ying HUANG, Weiwen ZHOU, Jing LIU, Yanning LI, Sha LI. Epidemic characteristics and spatial-temporal clustering of hepatitis B in children aged under 15 years in Guangxi Zhuang Autonomous Region, 2009–2023[J]. Chinese Journal of Public Health, 2025 , 41 (8) : 954 -960 . DOI: 10.11847/zgggws1147558
Year 2025 volume 41 Issue 8
61
21
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Article Info
doi: 10.11847/zgggws1147558
  • Receive Date:2025-03-31
  • Online Date:2026-10-25
  • Published:2025-08-10
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History
  • Received:2025-03-31
  • Revised:2025-06-11
  • Accepted:2025-08-02
Affiliations
    1School of Public Health, Guangxi Medical University, Nanning 530021, China
    2Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China
    3Guangxi Key Laboratory for the Prevention and Control of Viral Hepatitis, Nanning 530028, China

Corresponding:

LI Yanning, E-mail:
LI Sha, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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