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A new briarane-type diterpenoid from the South China Sea gorgonian Junceella fragilis
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Shou-mao SHEN1, 2, Yue-wei GUO1, *, Xu-wen LI1, *
Acta Pharmaceutica Sinica | 2020, 55(7) : 1661 - 1665
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Acta Pharmaceutica Sinica | 2020, 55(7): 1661-1665
Original Articles
A new briarane-type diterpenoid from the South China Sea gorgonian Junceella fragilis
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Shou-mao SHEN1, 2, Yue-wei GUO1, *, Xu-wen LI1, *
Affiliations
  • 1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • 2. School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China
Published: 2020-07-12 doi: 10.16438/j.0513-4870.2020-0963
Outline
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The chemical constituents of gorgonian Junceella fragilis Ridley, collected from Ximao Island, the South China Sea, were investigated. A new briarane-type diterpenoid, named fragilide Y (1), together with five known compounds (2-6), namely fragilide D (2), cholesterol (3), ergosterol peroxide (4), 2'-deoxythymidine (5) and cis-thyminenol (6), were isolated from the acetone extract of J. fragilis. The structure of the new compound 1 was elucidated by extensive spectroscopic analysis, while the known compounds were identified by comparison with the reported data. In bioassay, none of these compounds displayed obvious anti-inflammatory and cytotoxic effects.

gorgonian  /  Junceella fragilis  /  briarane-type diterpenoid  /  South China Sea
Shou-mao SHEN, Yue-wei GUO, Xu-wen LI. A new briarane-type diterpenoid from the South China Sea gorgonian Junceella fragilis[J]. Acta Pharmaceutica Sinica, 2020 , 55 (7) : 1661 -1665 . DOI: 10.16438/j.0513-4870.2020-0963
Year 2020 volume 55 Issue 7
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Article Info
doi: 10.16438/j.0513-4870.2020-0963
  • Receive Date:2020-06-14
  • Online Date:2026-01-21
  • Published:2020-07-12
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History
  • Received:2020-06-14
  • Revised:2020-06-28
Funding
Affiliations
    1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
    2. School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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