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A new cytochalasan compound from endophyte Chaetomium globosum WQ in Imperata cylindrical
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Wen-jing XIA1, 2, Xing-qin CAO1, 2, Qin LIU3, Sha-sha WANG1, 2, Li SHEN1, 2, *
Acta Pharmaceutica Sinica | 2020, 55(5) : 967 - 970
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Acta Pharmaceutica Sinica | 2020, 55(5): 967-970
• Original Articles •
A new cytochalasan compound from endophyte Chaetomium globosum WQ in Imperata cylindrical
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Wen-jing XIA1, 2, Xing-qin CAO1, 2, Qin LIU3, Sha-sha WANG1, 2, Li SHEN1, 2, *
Affiliations
  • 1. Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China
  • 2. Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001, China
  • 3. Jiangsu Lixiahe Institute of Agricultural Science, Yangzhou 225007, China
Published: 2020-05-15 doi: 10.16438/j.0513-4870.2019-0966
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Chaetomium globosum WQ, an endophyte derived from Imperata cylindrical, can produce abundant cytochalasan compounds through solid state fermentation. Based on previous research and guided by 1H NMR spectrum and TLC, a new cytochalasan compound was isolated from the ethyl acetate extract of a solid culture of C. globosum WQ using silica gel column chromatography, gel filtration over Sephadex LH-20 and HPLC. The new compound was characterized as 20-iso-chaetoglobosin E (1) by a combination of spectroscopic (HR-MS, 1D and 2D NMR) analyses.

Imperata cylindrical  /  endophyte  /  Chaetomium globosum  /  secondary metabolites  /  20-iso-chaetoglobosin E  /  cytochalasan compound
Wen-jing XIA, Xing-qin CAO, Qin LIU, Sha-sha WANG, Li SHEN. A new cytochalasan compound from endophyte Chaetomium globosum WQ in Imperata cylindrical[J]. Acta Pharmaceutica Sinica, 2020 , 55 (5) : 967 -970 . DOI: 10.16438/j.0513-4870.2019-0966
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Article Info
doi: 10.16438/j.0513-4870.2019-0966
  • Receive Date：2019-12-03
  • Online Date：2026-01-21
  • Published：2020-05-15
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History
  • Received：2019-12-03
  • Revised：2020-02-02
Funding
Affiliations
    1. Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China
    2. Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou 225001, China
    3. Jiangsu Lixiahe Institute of Agricultural Science, Yangzhou 225007, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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