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Research progress on the role and mechanism of Wnt signaling pathway in neuropathic pain
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Bi-rui WEN1, 2, Zhi-ling ZHANG2, Nai-hong CHEN1, 2, *
Acta Pharmaceutica Sinica | 2020, 55(2) : 201 - 207
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Acta Pharmaceutica Sinica | 2020, 55(2): 201-207
• Reviews •
Research progress on the role and mechanism of Wnt signaling pathway in neuropathic pain
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Bi-rui WEN1, 2, Zhi-ling ZHANG2, Nai-hong CHEN1, 2, *
Affiliations
  • 1. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
  • 2. Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2020-02-12 doi: 10.16438/j.0513-4870.2019-0624
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Neuropathic pain (NP), as a kind of chronic pain syndrome, seriously endangers the quality of life of patients, and the pathogenesis is complex, clinical treatment is limited, and it is easy to relapse. More and more reports have found that Wnt signaling pathway is closely related to the occurrence and development of neuropathic pain. Therefore, further study of the Wnt signaling pathway may provide useful ideas for exploring the pathogenesis of NP and discovering effective treatment methods. This article reviews the role and mechanism of Wnt signaling pathway in neuropathic pain.

neuropathic pain  /  Wnt signaling pathway  /  Wnt/β-catenin  /  hyperpathia  /  allodynia
Bi-rui WEN, Zhi-ling ZHANG, Nai-hong CHEN. Research progress on the role and mechanism of Wnt signaling pathway in neuropathic pain[J]. Acta Pharmaceutica Sinica, 2020 , 55 (2) : 201 -207 . DOI: 10.16438/j.0513-4870.2019-0624
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Article Info
doi: 10.16438/j.0513-4870.2019-0624
  • Receive Date：2019-08-02
  • Online Date：2026-01-20
  • Published：2020-02-12
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History
  • Received：2019-08-02
  • Revised：2019-09-30
Funding
Affiliations
    1. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
    2. Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
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Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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