收藏切换
Research on three-dimensional ordered porous carbon-based materials prepared from Acanthopanax senticosus traditional Chinese medicine residues and their drug loading performance
收藏切换
PDF
De-sheng WANG, Jia-xin FAN, Ri-qing CHENG, Shi-kui WU, Lai-bing WANG, Jia-hao SHI, Ting-ting CHEN, Qin-fang HE, Chang-jin XU*, Hui-qing GUO*
Acta Pharmaceutica Sinica | 2024, 59(10) : 2857 - 2863
Less
收藏切换
Acta Pharmaceutica Sinica | 2024, 59(10): 2857-2863
Research on three-dimensional ordered porous carbon-based materials prepared from Acanthopanax senticosus traditional Chinese medicine residues and their drug loading performance
Full
De-sheng WANG, Jia-xin FAN, Ri-qing CHENG, Shi-kui WU, Lai-bing WANG, Jia-hao SHI, Ting-ting CHEN, Qin-fang HE, Chang-jin XU*, Hui-qing GUO*
Affiliations
  • School of Pharmacy, Inner Mongolia Medical University, Hohhot 010110, China
Published: 2024-10-12 doi: 10.16438/j.0513-4870.2024-0286
Outline
收藏切换

Three-dimensional ordered porous carbon materials exhibit potential application prospects as excellent drug supports in drug delivery systems due to their high specific surface area, tunable pore structure, and excellent biocompatibility. In this study, three-dimensional ordered porous carbon materials were prepared using Acanthopanax senticosus herbal residues as raw material and KOH as activating agent through a one-step pyrolysis method. The prepared carbon-based material was systematically characterized by powder X-ray diffraction, scanning electron microscopy, N2 adsorption-desorption and Fourier-transform infrared spectroscopy. The results show that the three-dimensional ordered porous carbon materials prepared with KOH as the activator via pyrolysis possess abundant functional groups, high porosity, and high specific surface area, with a specific surface area of 1 471.6 m2·g-1. The three-dimensional ordered porous carbon materials prepared at 800 ℃ exhibits a high drug loading capacity (78.0%) and drug release rate (86.8%) for 5-fluorouracil. Three-dimensional orderly porous carbon materials show significant application advantages in drug construction, and their high specific surface area and adjustable pore size structure significantly improve the drug load rate and drug release rate, providing a solid foundation for the development of efficient and accurate drug delivery system.

Chinese medicine residue  /  Acanthopanax senticosus  /  three-dimensional ordered porous carbon material  /  drug loading performance  /  drug release performance
De-sheng WANG, Jia-xin FAN, Ri-qing CHENG, Shi-kui WU, Lai-bing WANG, Jia-hao SHI, Ting-ting CHEN, Qin-fang HE, Chang-jin XU, Hui-qing GUO. Research on three-dimensional ordered porous carbon-based materials prepared from Acanthopanax senticosus traditional Chinese medicine residues and their drug loading performance[J]. Acta Pharmaceutica Sinica, 2024 , 59 (10) : 2857 -2863 . DOI: 10.16438/j.0513-4870.2024-0286
Year 2024 volume 59 Issue 10
PDF
191
85
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2024-0286
  • Receive Date:2024-04-02
  • Online Date:2025-11-24
  • Published:2024-10-12
Article Data
Affiliations
History
  • Received:2024-04-02
  • Revised:2024-07-15
Funding
Affiliations
    School of Pharmacy, Inner Mongolia Medical University, Hohhot 010110, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2024-0286
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT