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A novel nitro-substituted bisabolane-type sesquiterpenoid from Curcuma longa
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Fu CHEN1, 3, Zhi-hao TIAN1, 3, Guang-xu WU1, 3, Fei LIU1, 3, *, Liang XIONG1, 2, 3, *
Acta Pharmaceutica Sinica | 2025, 60(5) : 1474 - 1478
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Acta Pharmaceutica Sinica | 2025, 60(5): 1474-1478
• Original Articles •
A novel nitro-substituted bisabolane-type sesquiterpenoid from Curcuma longa
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Fu CHEN1, 3, Zhi-hao TIAN1, 3, Guang-xu WU1, 3, Fei LIU1, 3, *, Liang XIONG1, 2, 3, *
Affiliations
  • 1. State Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • 2. College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
  • 3. Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Published: 2025-05-12 doi: 10.16438/j.0513-4870.2024-1268
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The 95% ethanol extract of Curcuma longa was isolated and purified by silica gel column chromatography, polyamide column chromatography, preparative thin layer chromatography and semi-preparative HPLC. Then, the structures of the obtained compounds were identified by HR-MS, IR, and NMR. Absolute configuration of the new compound was determined by calculating ECD. Finally, two bisabolane-type sesquiterpenoids were obtained from C. longa and identified as (7S)-1,3,5,10-bisabolatetraen-3-nitro-9-one (1) and turmeronol A (2). Compound 1 was a novel nitro-substituted bisabolane-type sesquiterpenoid.

Curcuma longa L.  /  isolation and identification  /  bisabolane-type sesquiterpenoid  /  nitro group
Fu CHEN, Zhi-hao TIAN, Guang-xu WU, Fei LIU, Liang XIONG. A novel nitro-substituted bisabolane-type sesquiterpenoid from Curcuma longa[J]. Acta Pharmaceutica Sinica, 2025 , 60 (5) : 1474 -1478 . DOI: 10.16438/j.0513-4870.2024-1268
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Article Info
doi: 10.16438/j.0513-4870.2024-1268
  • Receive Date：2024-12-21
  • Online Date：2025-10-29
  • Published：2025-05-12
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History
  • Received：2024-12-21
  • Revised：2025-01-06
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Affiliations
    1. State Key Laboratory of Southwestern Chinese Medicine Resources, College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
    2. College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
    3. Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
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https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2024-1268
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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